Published Feb 04 2021

Do you really need IVF? A new online tool can help you weigh your options

People who want a baby and struggle to conceive often resort to in vitro fertilisation (IVF). While IVF has helped countless people have children, it’s expensive and comes with some risks.

But research shows some people with so-called “unexplained infertility” have a 30-40% chance of conceiving without treatment if they just keep trying for a bit longer.

So, how long should you wait before starting fertility treatment? This depends on a range of factors that might increase or decrease your chance of conceiving naturally, as well as your personal preferences for seeking treatment or not.

A new online guide can estimate your chance of conceiving with and without treatment. The free tool collects information based on what we understand to be the main factors affecting a woman’s chance of falling pregnant, with a view to informing decisions regarding fertility treatment.

Sometimes there’s no clear explanation

It’s recommended that women who have tried unsuccessfully for a baby for 12 months – or six months if they’re over 35 – seek medical advice. This is so the doctor can arrange for tests to determine whether there’s a reason for infertility.

If these tests show the woman’s fallopian tubes are blocked, or that the male partner has a very low sperm count, it’s best to go straight to IVF. In most cases, that’s the only way the couple will be able to get pregnant.

If your doctor finds no obvious problem, you have what’s called “unexplained” or “idiopathic” infertility.

It’s worth seeing a doctor if you’ve tried unsuccessfully to conceive for 12 months, or six months if you’re over 35. Photo: Shutterstock

Weighing your options

It can be very frustrating to be told there’s nothing wrong, when month after month goes by without pregnancy happening.

Although IVF might seem like the fastest option, it can be expensive, costing most people thousands of dollars. And like any medical procedure, IVF carries risks, particularly for women.

If your tests come back normal, it might be worth considering giving nature a bit more time, or trying a simpler form of infertility treatment, such as intrauterine insemination (IUI). This involves insertion of the male partner’s (or a donor’s) sperm into a woman’s uterus at, or just before, ovulation.

So which path is right for you? This is where the new online guide can help.


Read more: Shining a light on polycystic ovary syndrome


It’s built on evidence

Research tracking thousands of people with unexplained infertility has found many go on to have healthy babies naturally, or with the help of simple fertility treatment. In one study of more than 1200 couples with unexplained infertility, 25% conceived naturally within 12 months.

Of course, for some women conception will be more likely, and for some women it will be less likely.

Experts used the data from this research to develop the online guide. The personalised calculations are based on four factors that evidence indicates are most likely to affect the chance of pregnancy.

The most important factor that affects a woman’s chance of having a baby – naturally or with IVF – is her age. So what’s labelled unexplained infertility may in fact be age-related. While pregnancy can still happen, by age 40 a woman’s fertility is about half the level it was when she was 30.

Other factors include how long she's been trying for a baby (the likelihood of conception decreases with the duration of trying), whether she’s been pregnant before (women who have never previously conceived have a lower probability of achieving a pregnancy), and what proportion of the male partner’s sperm move normally (called “progressive motility” on a semen analysis report).


Read more: Considering using IVF to have a baby? Here's what you need to know


How does it work?

The guide is designed for heterosexual couples and for women who are trying to get pregnant with a known sperm donor, where:

  • the woman has regular menstrual cycles

  • the woman has at least one open fallopian tube

  • the woman is 42 or younger

  • the man has had a sperm test.

This new online tool aims to inform your decisions regarding fertility treatment. Photo: Shutterstock

Four questions ask about the four factors most likely to affect a woman’s chance of conception, described above.

The responses are then fed into the algorithm, which estimates the chance of pregnancy over the next 12 months in three different scenarios:

  • You just keep trying

  • You have six cycles of IUI

  • You have two cycles of IVF.

This information can help people consider their options and decide about next steps.

If your estimated chance of spontaneous pregnancy in the next 12 months is 30% or more, you have a good chance of avoiding the need for expensive fertility treatments. But if you’re not pregnant after six months, the guide suggests seeking advice from a fertility specialist about the next steps.

If your estimated chance without treatment is less than 30%, it’s best to see a fertility specialist as soon as possible.

A word of caution

While the guide can help you explore your options and consider next steps, the estimates it gives are based on averages of data from large studies of people with unexplained infertility.

This means it shouldn’t replace advice from a fertility specialist, who will hopefully use the available evidence to recommend the best way forward for you, considering your personal circumstances and preferences.


Read more: Women's fertility: Does 'egg timer' testing work, and what are the other options?


This article originally appeared on The Conversation.

About the Authors

  • Karin hammarberg

    Senior Research Fellow, School of Public Health and Preventive Medicine

    Karin is a Registered Nurse with 20 years of experience as clinical co-ordinator of IVF programs. Her PhD research examined the experience of birth and mothering after assisted conception. Karin's main research interests are fertility and preconception health promotion; the psychosocial aspects of infertility and infertility treatment; health and development of children born as a result of assisted conception; infertility care in resource-constrained settings, and women's health in midlife.

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