Christina trained as a physician scientist specialising in clinical haematology. She received a degree in Medicine from Melbourne University and consultant training in Haematology at the Alfred Hospital, Melbourne, and a PhD from Monash University. In 1999 Christina was appointed Professor and Head of the Department of Biochemistry and Molecular Biology at Monash University; in 2006 she became Head of the School of Biomedical Sciences, and in 2011 she became Monash’s Dean of Medicine.
The major research direction of her group is to characterise the metabolic pathways that regulate phosphoinositide signalling in human cancer. Her group was among the first to purify and clone the 5-phosphatases and to delineate the substrates for these important enzymes in cancer. More recently her group has investigated the functional role of inositol polyphosphate 3- and 4-phosphatases in various cell systems and human disease.